|Appearance:||White Or Yellowish Powder|
high performance binder HPMC Hypromellose,
refined cotton Eye Drops HPMC Hypromellose,
refined cotton hypromellose e15
Pharma Grade HPMC Hypromellose for Eye Drops
Name: Hypromellose or Hydroxypropyl Methyl Cellulose(HPMC,Hypromellose)
Appearance and properties: White or almost white fibrous or granular powder
Molecular Formula: [C6H7O2(OH)x-m-n (OCH3 )m (OCH2CH (OH)CH3 )n]x
HPMC, also known as hypromellose, is one of the non-ionic cellulose mixed ethers. It is a semi-synthetic, inactive, viscoelastic polymer, often used as a lubricant in ophthalmology, or as an excipient or excipient in oral medicine.HPMC is used as a precipitation inhibitor for solid dispersions in spray drying or hot melt extrusion formulations.
1.Cohesiveness (Binding property) :Hypromellose or HPMC , as a high performance binder , can also be used for molding food and medicine .
2. PH stability :The viscosity of an aqueous solution of HPMC is hardly affected by acid or alkali , and the product can develop an original viscosity in the range of 3 . 0~11 . 0 . Therefore , the solution viscosity tends to keep stable during prolonged storage ..
3. Film forming :Hypromellose or HPMC provides a strong , flexible and transparent film having a good barrier property against oil and grease . In food application , this property is often utilized for water retention and oil adsorption .
1.Appearance: white to yellowish powder
2.Viscosity Specification as below
|Level||Specific range (2% Sol.),mPa.s||Level||Specific range (2% Sol.),mPa.s|
|Loss on drying,%||5.0 max|
|Residue on ignition,%||1.5 max|
|Heavy metals, ppm||20 max|
|Arsenic, ppm||3 max|
|Viscosity(2% solution), mPa.s||In accordance with the viscosity specification as shown in table 2.|
Note: Any other special requirement for the product can be satisfied through the negotiation.
Hypromellose (HPMC) is a multi-purpose pharmaceutical excipient.
The high viscosity specification is widely used in the sustained and controlled release system of hydrophilic gel matrix. The low-viscosity grade is used as the main shell material in tablet coating and non-gelatin capsule formulations, and is also a commonly used binder in wet granulation.
Selection guide of products for pharmaceutical:
|Usage||Applicable type of the product||
|Creams, Gels, and Ointments||E-4000,F-4000,K-4000||1-5%|
|Ophthalmic Preparations||E-4000||01 .-0 . 5%|
|Eye drops preparations||F-4000, K-4000||0 . 1-0 . 5%|
|Suspending agent||E-4000, K-4000||1-2%|
|Tablets binder||E-5, F-50, K- 100||0 . 5-5%|
|Conventional Tablet Coating||E-5,E-15||0 . 5-5%|
|Conventional Wet Granulation||E-5,E-15||2-6%|
|Controlled Release Coatings||E-5,E-15||3-20%|
|Tablet coatings||E-5, E- 15, E-50||0 . 5-5%|
Controlled Release Matrix
|K- 100,000,K- 15,000,K-4000,E-4000||
Hypromellose or HPMC is packed in polyethylene bag enclosed in composite fiberboard drum . The standard packing is 25kg/drum
Loading Quantity in 20'FCL With Pallet: 9Tons
【Transportation and Storage】
The product should be kept in the original bag and stored in the dry and clean place far away from the source of heat and not put together with other chemicals .
The direct addition of the product to water causes the formation of lumps . Lumping results from incomplete wetting of the individual powder particles . Only the powder in contact with water dissolves and the formed gelatinous membrane prevents the remaining powder from dissolving , causing a delay in the dissolution time . The following three methods are recommended for dissolution without forming lumps . The most convenient method should be chosen according to the purpose of your application.
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