Product Details:
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Appearance: | White Or Yellowish Powder | Product Name: | Pharma Grade HPMC 15 Cps For Tablet Coating Similar To Methocel E15 |
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Raw Material: | Refined Cotton | Application: | Thickener, Emulsifier, Film-former, Binder, Dispersing Agent, Protective Colloids |
Advantage: | Good Water Retention, Stable | Sample: | 200g Free Sample Provide |
CAS No.: | 9004-65-3 | Packing: | 25kg/bag |
High Light: | Pharma Grade HPMC,9004-65-3 HPMC Pharma,Hydroxypropyl Methyl Cellulose 15 Cps |
Pharma Grade HPMC 15 cps for tablet Coating similar to methocel e15
【Introduction】
Name: Hydroxypropyl Methyl Cellulose(HPMC,Hypromellose)
Appearance and properties: White or almost white fibrous or granular powder
E Number:E464
CAS NO:9004-65-3
Molecular Formula: [C6H7O2(OH)x-m-n (OCH3 )m (OCH2CH (OH)CH3 )n]x
【Characteristics】
Hydroxypropyl methyl cellulose (HPMC) is a natural polymer materials as raw materials,through a series of chemical processing and prepared non-ionic cellulose,To meet the needs of environmental protection, Our product with high water retention, dispersion, good fineness, good work ability, easy dissolution characteristics
【Technical requirements】
1.Appearance: white to yellowish powder or granule
2.Techinical Specifications:
Items
|
Specifications | |||
HPMC | ||||
F | E | J | K | |
Loss on drying,% | 5.0 max | |||
Residue on ignition,% | 1.5 max | |||
Heavy metals, ppm | 20 max | |||
Arsenic, ppm | 3 max | |||
pH | 5.0~8.0 | |||
Bacterium | 1000cfu/gram Max | |||
Mold | 100cfu/gram Max | |||
Viscosity(2% solution), mPa.s | In accordance with the viscosity specification as shown in table 2. |
3.Viscosity Specification
Level | Specific range (2% Sol.),mPa.s | Level | Specific range (2% Sol.),mPa.s |
5 | 4~6 | 4000 | 3000~5600 |
15 | 12~18 | 8000 | 6000~9000 |
25 | 20~30 | 10,000 | 9000~12000 |
50 | 40~60 | 15,000 | 12000~18000 |
100 | 80~120 | 20,000 | 18000~30000 |
400 | 300~500 | 40,000 | 30000~50000 |
800 | 600~900 | 100,000 | 85000~130000 |
1500 | 1000~2000 | 200,000 | ≥180000 |
Note: Any other special requirement for the product can be satisfied through the negotiation.
【Application】
Pharmaceutical aid: HPMC is used as adhesive, solutizer in tablet, film-forming reagents in pharmaceutical coating,delayed-release and controlled-release tablets or capsules, thickener and water-binding agent in liquid formulation, component in eye drop.
Selection guide of products for pharmaceutical:
Usage | Applicable type of the product |
Typical Use Level |
Bulk Laxative | K-4000,K-100,000 | 3-30% |
Creams, Gels, and Ointments | E-4000,F-4000,K-4000 | 1-5% |
Ophthalmic Preparations | E-4000 | 01 .-0 . 5% |
Eye drops preparations | F-4000, K-4000 | 0 . 1-0 . 5% |
Suspending agent | E-4000, K-4000 | 1-2% |
Antacids | E-4000,K-4000,K-15000,F-4000 | 1-2% |
Tablets binder | E-5, F-50, K- 100 | 0 . 5-5% |
Conventional Tablet Coating | E-5,E-15 | 0 . 5-5% |
Conventional Wet Granulation | E-5,E-15 | 2-6% |
Controlled Release Coatings | E-5,E-15 | 3-20% |
Tablet coatings | E-5, E- 15, E-50 | 0 . 5-5% |
Controlled Release Matrix Tablets |
K- 100,000,K- 15,000,K-4000,E-4000 |
20-55% |
【Packaging】
pharma grade HPMC cellulose is packed in 2 layer LDPE bag and sealed in the Drum, it is very safe to store and transport. the standard packing is 25kg/drum
【Transportation and Storage】
The product should be kept in the original bag and stored in the dry and clean place far away from the source of heat and not put together with other chemicals .
The direct addition of the product to water causes the formation of lumps . Lumping results from incomplete wetting of the individual powder particles . Only the powder in contact with water dissolves and the formed gelatinous membrane prevents the remaining powder from dissolving , causing a delay in the dissolution time . The following three methods are recommended for dissolution without forming lumps . The most convenient method should be chosen according to the purpose of your application .
Contact Person: Mrs. Lannie Zhang
Tel: 86-021-54012006
Fax: 86-021-54012008