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Film Formimg Reagents Excipients Tablets HPMC Hypromellose

Basic Information
Place of Origin: China
Brand Name: Honest
Model Number: E5 E15 E4M K100M
Minimum Order Quantity: 500kgs
Packaging Details: 25kg/Drum
Delivery Time: 10-15days
Payment Terms: L/C, T/T, Western Union
Supply Ability: 500000KGS/Month
Detail Information
Produt Name: Excipients Tablets HPMC Hypromellose Appearance: White Or Yellowish Powder
Raw Material: Refined Cotton Application: Thickener, Emulsifier, Film-former, Binder, Dispersing Agent, Protective Colloids
Advantage: Good Water Retention, Stable Sample: 200g Free Sample Provide
High Light:

25kg per drum Hypromellose Hydroxypropyl Methylcellulose

,

25kg drum Hydroxypropyl Methylcellulose 2910

,

eye drop Hypromellose Hydroxypropyl Methylcellulose


Product Description

Introduction

Name: Hypromellose or Hydroxypropyl Methyl Cellulose(HPMC)

Appearance and properties: white or almost white fibrous or granular powder 

CAS NO:9004-65-3

E Number:E464

Abbreviation: HPMC

Molecular Formula: [C6H7O2(OH)x-m-n (OCH3 )m (OCH2CH (OH)CH3 )n]x

 

 

Film Formimg Reagents  Excipients Tablets HPMC Hypromellose 0

 

Characteristics

 

Hypromellose or Hydroxypropyl methyl cellulose (HPMC) is an odorless and tasteless, white to slightly off-white, fibrous or granular, free-flowing powder that is a synthetic modification of the natural polymer, cellulose.

 

Properties

1. Cohesiveness (Binding property) :Hypromellose or HPMC , as a high performance binder , can also be used for molding food and medicine .

2. Resistance to salting out :Hypromellose or HPMC is a nonionic cellulose ether and it is not a polyelectrolyte . The aqueous solution of HPMC is comparatively stable even in the presence of metal salts or organic electrolytes . However , when the concentration of electrolytes exceeds a certain limit , gelation and precipitation may result .

3. PH stability :The viscosity of an aqueous solution of Hypromellose or HPMC is hardly affected by acid or alkali , and the product can develop an original viscosity in the range of 3 . 0~11 . 0 . Therefore , the solution viscosity tends to keep stable during prolonged storage ..

 

4. Film forming :Hypromellose or HPMC provides a strong , flexible and transparent film having a good barrier property against oil and grease . In food application , this property is often utilized for water retention and oil adsorption .

 

5. Water retention :Hypromellose or HPMC is a high effective water retention agent . Its pharmaceutical grade product can be widely used in food , cosmetics and many other fields .

 

Technical requirements

 

1. Appearance: white to yellowish powder or grains.

 

2. Viscosity Specification as below

 

Film Formimg Reagents  Excipients Tablets HPMC Hypromellose 1

 

3. Techinical Specifications:

Film Formimg Reagents  Excipients Tablets HPMC Hypromellose 2

   

 

3.Viscosity Specification

 

Film Formimg Reagents  Excipients Tablets HPMC Hypromellose 1

 

Note: Any other special requirement for the product can be satisfied through the negotiation.

 

Application

Pharmaceutical aid: Hypromellose or HPMC is used as adhesive, solutizer in tablet, film-forming reagents in pharmaceutical coating,delayed-release and controlled-release tablets or capsules, thickener and water-binding agent in liquid formulation, component in eye drop.

 

Selection guide of products for pharmaceutical:

 

Usage Applicable type of the product

Typical Use

Level

Bulk Laxative K-4000,K-100,000 3-30%
Creams, Gels, and Ointments E-4000,F-4000,K-4000 1-5%
Ophthalmic Preparations E-4000 01 .-0 . 5%
Eye drops preparations F-4000, K-4000 0 . 1-0 . 5%
Suspending agent E-4000, K-4000 1-2%
Antacids E-4000,K-4000,K-15000,F-4000 1-2%
Tablets binder E-5, F-50, K- 100 0 . 5-5%
Conventional Tablet Coating E-5,E-15 0 . 5-5%
Conventional Wet Granulation E-5,E-15 2-6%
Controlled Release Coatings E-5,E-15 3-20%
Tablet coatings E-5, E- 15, E-50 0 . 5-5%

Controlled Release Matrix

Tablets

K- 100,000,K- 15,000,K-4000,E-4000

 

20-55%

 

 

Packaging

Hypromellose or HPMC is packed in polyethylene bag enclosed in composite fiberboard drum . The standard packing is 25kg/drum 

Transportation and Storage

 

The product should be kept in the original bag and stored in the dry and clean place far away from the source of heat and not put together with other chemicals .

The direct addition of the product to water causes the formation of lumps . Lumping results from incomplete wetting of the individual powder particles . Only the powder in contact with water dissolves and the formed gelatinous membrane prevents the remaining powder from dissolving , causing a delay in the dissolution time . The following three methods are recommended for dissolution without forming lumps . The most convenient method should be chosen according to the purpose of your application .

 

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