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Refined Cotton Coating HPMC Uses In Pharmaceuticals

Basic Information
Place of Origin: China
Brand Name: Honest
Model Number: E5 E15 E4M K100M
Minimum Order Quantity: 500kgs
Packaging Details: 25kg/Drum
Delivery Time: 10-15days
Payment Terms: L/C, T/T, Western Union
Supply Ability: 500000KGS/Month
Detail Information
Product Name: Hypromellose For Artificial Tears Solution Appearance: White Or Yellowish Powder
Raw Material: Refined Cotton Application: Thickener, Emulsifier, Film-former, Binder, Dispersing Agent, Protective Colloids
Advantage: Good Water Retention, Stable Sample: 200g Free Sample Provide
High Light:

USP HPMC Uses In Pharmaceuticals

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9004 65 3 Hydroxypropyl Methylcellulose For Drops

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E5 HPMC Uses In Pharmaceuticals


Product Description

Introduction

Name: Hydroxypropyl Methyl Cellulose(HPMC,Hypromellose)

Appearance and properties: White or off-white granule or powder

CAS NO:9004-65-3

Molecular Formula: [C6H7O2(OH)x-m-n (OCH3 )m (OCH2CH (OH)CH3 )n]x

 

 

Refined Cotton Coating HPMC Uses In Pharmaceuticals 0

 

Characteristics

 

Hydroxypropyl methyl cellulose (HPMC) is a natural polymer materials as raw materials,through a series of chemical processing and prepared non-ionic cellulose. It contains almost methyl cellulose(MC) of all the performance, your first choice for production of high quality building materials additives.

 

Properties

 

Ø Cohesion

Ø Dimensional stability

Ø Water retention capacity

Ø Salt-resistant low ash powder

Ø pH stability

Ø Excellent film-forming ability

Ø Thickening ability

Ø Extensive enzyme resistance

 

Technical requirements

 

1.Appearance: white to yellowish powder 

 

2.Viscosity Specification as below

 

Refined Cotton Coating HPMC Uses In Pharmaceuticals 1

 

3.Techinical Specifications:

Refined Cotton Coating HPMC Uses In Pharmaceuticals 2

   

 

Note: Any other special requirement for the product can be satisfied through the negotiation.

 

Application

Pharmaceutical aid: HPMC is used as adhesive, solutizer in tablet, film-forming reagents in pharmaceutical coating,delayed-release and controlled-release tablets or capsules, thickener and water-binding agent in liquid formulation, component in eye drop.

 

The high viscosity specification is widely used in the sustained and controlled release system of hydrophilic gel matrix. The low-viscosity grade is used as the main shell material in tablet coating and non-gelatin capsule formulations, and is also a commonly used binder in wet granulation.

 

Selection guide of products for pharmaceutical:

 

Usage Applicable type of the product

Typical Use

Level

Bulk Laxative K-4000,K-100,000 3-30%
Creams, Gels, and Ointments E-4000,F-4000,K-4000 1-5%
Ophthalmic Preparations E-4000 01 .-0 . 5%
Eye drops preparations F-4000, K-4000 0 . 1-0 . 5%
Suspending agent E-4000, K-4000 1-2%
Antacids E-4000,K-4000,K-15000,F-4000 1-2%
Tablets binder E-5, F-50, K- 100 0 . 5-5%
Conventional Tablet Coating E-5,E-15 0 . 5-5%
Conventional Wet Granulation E-5,E-15 2-6%
Controlled Release Coatings E-5,E-15 3-20%
Tablet coatings E-5, E- 15, E-50 0 . 5-5%

Controlled Release Matrix

Tablets

K- 100,000,K- 15,000,K-4000,E-4000

 

20-55%

 

Refined Cotton Coating HPMC Uses In Pharmaceuticals 3

Packaging

pharma grade HPMC cellulose is packed in 2 layer LDPE bag and sealed in the Drum, it is very safe to store and transport. the standard packing is 25kg/drum, one 20' container could 9000kg

 

 

Transportation and Storage

 

The product should be kept in the original bag and stored in the dry and clean place far away from the source of heat and not put together with other chemicals .

The direct addition of the product to water causes the formation of lumps . Lumping results from incomplete wetting of the individual powder particles . Only the powder in contact with water dissolves and the formed gelatinous membrane prevents the remaining powder from dissolving , causing a delay in the dissolution time . The following three methods are recommended for dissolution without forming lumps . The most convenient method should be chosen according to the purpose of your application .

 

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