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Product Details:
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| Appearance: | White Or Yellowish Powder | Product Name: | CAS NO 9004 65 3 Pharma Grade HPMC |
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| Raw Material: | Refined Cotton | Application: | Thickener, Emulsifier, Film-former, Binder, Dispersing Agent, Protective Colloids |
| Advantage: | Good Water Retention, Stable | Sample: | 200g Free Sample Provide |
| CAS No.: | 9004-65-3 | Packing: | 25kg/bag |
| High Light: | compressible tablets Pharma Grade HPMC,Honest compressible tablets 9004 65 3,K100M Pharma Grade HPMC |
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【Introduction】
Name: Hydroxypropyl Methyl Cellulose(HPMC,Hypromellose)
Appearance and properties: White or almost white fibrous or granular powder
E Number:E464
CAS NO:9004-65-3
Molecular Formula: [C6H7O2(OH)x-m-n (OCH3 )m (OCH2CH (OH)CH3 )n]x
【Characteristics】
Hydroxypropyl methyl cellulose (HPMC) is a natural polymer materials as raw materials,through a series of chemical processing and prepared non-ionic cellulose,To meet the needs of environmental protection, Our product with high water retention, dispersion, good fineness, good work ability, easy dissolution characteristics
Properties
1 . Resistance to salting out :HPMC is a nonionic cellulose ether and it is not a polyelectrolyte . The aqueous solution of HPMC is comparatively stable even in the presence of metal salts or organic electrolytes . However , when the concentration of electrolytes exceeds a certain limit , gelation and precipitation may result .
2.HPMC also has the characteristics of thickening ability, salt resistance, low ash powder, pH stability, water retention, dimensional stability, excellent film-forming properties, and extensive enzyme resistance, dispersibility, and adhesion.
3 . Film forming :HPMC provides a strong , flexible and transparent film having a good barrier property against oil and grease . In food application , this property is often utilized for water retention and oil adsorption .
4. Water retention :HPMC is a high effective water retention agent . Its pharmaceutical grade product can be widely used in food , cosmetics and many other fields .
5. Solubility: soluble in water and some solvents, such as ethanol/water, propanol/water in appropriate proportions. The aqueous solution has surface activity. High transparency and stable performance. Different specifications of products have different gel temperatures, and solubility changes with viscosity. The lower the viscosity, the greater the solubility. Different specifications of HPMC have certain differences in performance. The dissolution of HPMC in water is not affected by pH.
【Technical requirements】
1.Appearance: white to yellowish powder or granule
2.Viscosity Specification as below
3.Techinical Specifications:
3.Viscosity Specification
Note: Any other special requirement for the product can be satisfied through the negotiation.
【Application】
Pharmaceutical aid: HPMC is used as adhesive, solutizer in tablet, film-forming reagents in pharmaceutical coating,delayed-release and controlled-release tablets or capsules, thickener and water-binding agent in liquid formulation, component in eye drop.
Selection guide of products for pharmaceutical:
| Usage | Applicable type of the product |
Typical Use Level |
| Bulk Laxative | K-4000,K-100,000 | 3-30% |
| Creams, Gels, and Ointments | E-4000,F-4000,K-4000 | 1-5% |
| Ophthalmic Preparations | E-4000 | 01 .-0 . 5% |
| Eye drops preparations | F-4000, K-4000 | 0 . 1-0 . 5% |
| Suspending agent | E-4000, K-4000 | 1-2% |
| Antacids | E-4000,K-4000,K-15000,F-4000 | 1-2% |
| Tablets binder | E-5, F-50, K- 100 | 0 . 5-5% |
| Conventional Tablet Coating | E-5,E-15 | 0 . 5-5% |
| Conventional Wet Granulation | E-5,E-15 | 2-6% |
| Controlled Release Coatings | E-5,E-15 | 3-20% |
| Tablet coatings | E-5, E- 15, E-50 | 0 . 5-5% |
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Controlled Release Matrix Tablets |
K- 100,000,K- 15,000,K-4000,E-4000 |
20-55% |
【Packaging】
pharma grade HPMC cellulose is packed in 2 layer LDPE bag and sealed in the Drum, it is very safe to store and transport. the standard packing is 25kg/drum
【Transportation and Storage】
The product should be kept in the original bag and stored in the dry and clean place far away from the source of heat and not put together with other chemicals .
The direct addition of the product to water causes the formation of lumps . Lumping results from incomplete wetting of the individual powder particles . Only the powder in contact with water dissolves and the formed gelatinous membrane prevents the remaining powder from dissolving , causing a delay in the dissolution time . The following three methods are recommended for dissolution without forming lumps . The most convenient method should be chosen according to the purpose of your application .
Contact Person: Mrs. Lannie Zhang
Tel: 86-021-54012006
Fax: 86-021-54012008
