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Product Details:
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| Product Name: | Hypromellose Hydroxypropyl Methyl Cellulose | Appearance: | White Or Yellowish Powder |
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| Raw Material: | Refined Cotton | Application: | Thickener, Emulsifier, Film-former, Binder, Dispersing Agent, Protective Colloids |
| Advantage: | Good Water Retention, Stable | Sample: | 200g Free Sample Provide |
| High Light: | Honest Pharma Grade Hydroxypropyl Methyl Cellulose,Cas Number 9004 65 3,Hypromellose Hydroxypropyl Methyl Cellulose |
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【Introduction】
Name: Hydroxypropyl Methyl Cellulose(HPMC)
Appearance and properties: White or off-white granule or powder
CAS NO:9004-65-3
Particle size; 100 mesh pass rate is greater than 98.5%; 80 mesh pass rate is 100%. Special specifications have a particle size of 40-60 mesh.
Molecular Formula: [C6H7O2(OH)x-m-n (OCH3 )m (OCH2CH (OH)CH3 )n]x
【Characteristics】
Hydroxypropyl methyl cellulose (HPMC) is a natural polymer materials as raw materials,through a series of chemical processing and prepared non-ionic cellulose.
【Properties】
1. Appearance
HPMC is an off-white substance in powdered form.
2. Discoloration temperature
It ranges from 190-200 ℃.
3. Carbonization temperature
HPMC carbonizes at a temperature between 280-300 ℃.
4. Surface tension
A 2% aqueous solution is 42-56 dyn/cm.
5. Visual density
Visual density ranges from 0.25-0.70g/cm (but usually about 0.5g/cm) and specific gravity ranges from 1.26-1.31.
6. Particle size
The particle size of special specifications ranges from 40 to 60 meshes. 100 mesh pass rate is more than 98.5% while the 80 mesh pass rate is 100%.
7. Solubility
HPM is highly soluble in water as well as other solvents, such as propanol, ethanol, etc.
【Technical requirements】
1.Appearance: white to yellowish powder
2.Viscosity Specification as below
3.Techinical Index:
Note: Any other special requirement for the product can be satisfied through the negotiation.
【Application】
Pharmaceutical aid: HPMC is used as adhesive, solutizer in tablet, film-forming reagents in pharmaceutical coating,delayed-release and controlled-release tablets or capsules, thickener and water-binding agent in liquid formulation, component in eye drop.
Selection guide of products for pharmaceutical:
| Usage | Applicable type of the product |
Typical Use Level |
| Bulk Laxative | K-4000,K-100,000 | 3-30% |
| Creams, Gels, and Ointments | E-4000,F-4000,K-4000 | 1-5% |
| Ophthalmic Preparations | E-4000 | 01 .-0 . 5% |
| Eye drops preparations | F-4000, K-4000 | 0 . 1-0 . 5% |
| Suspending agent | E-4000, K-4000 | 1-2% |
| Antacids | E-4000,K-4000,K-15000,F-4000 | 1-2% |
| Tablets binder | E-5, F-50, K- 100 | 0 . 5-5% |
| Conventional Tablet Coating | E-5,E-15 | 0 . 5-5% |
| Conventional Wet Granulation | E-5,E-15 | 2-6% |
| Controlled Release Coatings | E-5,E-15 | 3-20% |
| Tablet coatings | E-5, E- 15, E-50 | 0 . 5-5% |
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Controlled Release Matrix Tablets |
K- 100,000,K- 15,000,K-4000,E-4000 |
20-55% |
【Packaging】
pharma grade HPMC cellulose is packed in 2 layer LDPE bag and sealed in the Drum, it is very safe to store and transport. the standard packing is 25kg/drum, one 20' container could 9000kg
【Transportation and Storage】
The product should be kept in the original bag and stored in the dry and clean place far away from the source of heat and not put together with other chemicals .
The direct addition of the product to water causes the formation of lumps . Lumping results from incomplete wetting of the individual powder particles . Only the powder in contact with water dissolves and the formed gelatinous membrane prevents the remaining powder from dissolving , causing a delay in the dissolution time . The following three methods are recommended for dissolution without forming lumps . The most convenient method should be chosen according to the purpose of your application .
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