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Product Details:
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| Appearance: | White Or Yellowish Powder | Raw Material: | Refined Cotton |
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| Product Name: | OEM Ethyl Cellulose Pharmaceutical Use | Function: | Thickener, Emulsifier, Film-former, Binder, Dispersing Agent |
| Certification: | COA MSDS | ||
| High Light: | N50 Carboxymethyl Ethyl Cellulose,Pharmaceutical Methyl Hydroxy Ethyl Cellulose,USP Ethyl Hydroxyethyl Cellulose |
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Pharmaceutical Applicaion N7 N10 N20 N50 Ethyl Cellulose USP EP
EC is a naturally occurring polymer produced from wood pulp or cotton by treatment with alkali and then ethylation of the alkali cellulose with ethyl chloride.
Different EC grade can be produced by controlling the substitution of ethoxyl groups.
【Introduction】
Name: Ethyl Cellulose
Abbreviation: EC
Structural formula:
In the formula , n stands for degree of polymerization and R for –H or –C2H5.
【Characteristics】
Ethyl Cellulose is a white to light yellowish, oderless and tastless, non-ionic polymer powder derived from cellulose through a series of chemical and physical processes.
【Solubility 】
In water
Practically insoluble in water and it is the only modified cellulose not soluble in water but soluble in ethanol.
In organic Solvents
Insoluble in glycerol and in propane-1,2-diol.
Its solubility in varying proportions in certain organic solvents depending upon the ethoxyl content:
Less than 46–48%: freely soluble in tetrahydrofuran, in methyl acetate, in chloroform and in aromatic hydrocarbon ethanol mixtures.
46–48% or more: freely soluble in ethanol, in methanol, in toluene, in chloroform and in ethyl acetate.
【Technical requirements】
1. Appearance: White or even yellowing powder.
2. Technical Index
Table 1
| Item | Index | ||
| K type | N type | T type | |
| Content of ethoxy, % | 45.0~47.9 | 48.0~49.5 | 49.6~51.0 |
| Viscosity, mPas | Conform to the requirements of table 2 | ||
| Residue on ignition, % | 0.4 Max | ||
| Loss on drying % | 3.0 Max | ||
| Heavy metal ppm | 20 Max | ||
| Arsenic ppm | 3 Max | ||
| Bacterium | 1000cfu/gram Max | ||
| Mold | 100cfu/gram Max | ||
3. Viscosity Specification
| Level | Specific range | Level | Specific range |
| 4 | 3.0～5.5 | 45 | 41～49 |
| 7 | 6.0～8.5 | 55 | 51～60 |
| 10 | 9.0～12.5 | 70 | 62～74 |
| 15 | 13～ 16 | 90 | 80~90 |
| 20 | 18～22 | 100 | 91～110 |
Note: Provided that buyers have other
【Application】
Due to its insolubility in water, ethyl cellulose is mainly used as tablet adhesive and thin film coating material, etc. It is also used as retarding agent for aggregate to make various types of aggregate slow-release pills; as slow-release agent or slow-release pills for compound material when making coat; as microcapsule material to make the medical effect release continuously, and avoid the preaction of water soluble medicine.
It can be too used in any type of medicine as dispersing agent, stabilizer and water retention agent to prevent medicine from absorption and deterioration, enhance the safe storage and stability of pills.
It can even be used as adhesive, slow-release agent and moisture-repellant agent for vitamine pills and mineral pills.
Selection guide of products for pharmaceutical:
| Usage | Applicable type ofthe product | Typical Use Level |
| Controlled Release Coatings | EN-4,EN-7,EN-10 | 3-20% |
| Microencapsulation | EN-20,EN-45,EN-100 | 10-20% |
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Solvent-Based Coating for |
All N Type |
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| Direct Compression Granulation | EN-7, EN-10, EN-100 | 5-40% |
| Solvent-Based Granulation | EN-10,EN-20,EN-45 | 1-6% |
【Instruction for usage】
While padding, add Ethyl Cellulose slowly into the container with solvent until it is fully wetted and dissolved.
【Package】
It is packed in paper bags, fiberboard boxes or drums lined with PVC bags. Net weight per package: 10kg/20kg/50kg
【Instruction for storage】
Seal it and store in dry place.
【Our team】
Contact Person: Mrs. Lannie Zhang
Tel: 86-021-54012006
Fax: 86-021-54012008
