Pharma klasën HPMC

Përshkrim i shkurtër:

Hydroxypropyl methyl cellulose (HPMC; CAS No. 9004-65-3) is an odorless and tasteless, white to slightly off-white, fibrous or granular, free-flowing powder that is a synthetic modification of the natural polymer, cellulose. Hydroxypropyl methyl cellulose has become one of the largest pharmaceutical excipients because it possesses the advantages of other complementary makings don’t have. Advantages of HPMC 1. Chemical inertness HPMC is a kind of non-ionic cellulose ether, whose solution...


  • Min.urdhër Sasia: 20 kg (etil celuloza)
  • Furnizimi Aftësia: 30000 ton / vit (Hydropropyl Methyl Celuloza); 5000 ton / vit (hidroksietil Celuloza); 30.000 ton / vit (Carboxymethyline celuloza); 600 ton / vit (etilik Celuloza); 10000 ton / vit vetë-leveling kompleks grumbull master
  • Port: Shanghai
  • Termat pagesës: L / C, D / A, D / P, T / T
  • Detail Product

    Produkt Tags

    Hydroxypropyl methyl cellulose (HPMC ; CAS No. 9004-65-3) is an odorless and tasteless, white to slightly off-white, fibrous or granular, free-flowing powder that is a synthetic modification of the natural polymer, cellulose.

    Hydroxypropyl methyl cellulose has become one of the largest pharmaceutical excipients because it possesses the advantages of other complementary makings don’t have.

    Advantages of HPMC

    1. Chemical inertness

    HPMC is a kind of non-ionic cellulose ether, whose solution doesn’t take ionic charge and don’t react with metal salt or ionic organics. So there is no reaction between it and other materials during the preparation.

    2. Stability

    it is relatively stable in acid and alkali, and providing good viscosity stability between pH3 ~ 11 during long-term storage. Aqueous solutions are comparatively enzyme-resistant. Preparation materials using HPMC, its quality and stability is better than the traditional materials (dextrin, starch, etc.).

    3. Safety

    HPMC is generally regarded as a nontoxic and non-irritating material, The WHO has not specified an acceptable daily intake for HPMC since the levels consumed were not considered to represent a hazard to health.

    4. Viscosity can be regulatory

    The derivatives of different viscosity of HPMC can complex with each other according to the different proportion. Its viscosity can be change according to certain rules, and has a good linear relationship, so it can be chosen accord- ing to requirements in terms of proportion.

    5. Metabolism inertia

    HPMC is not absorbed and metabolized in the body, and cannot give heat, so it is a safe medicinal preparation ma- terial.

    6. Soluble in cold water

    Soluble in cold water under 40 ℃ or 70% ethanol, practically insoluble in hot water but gelation.

    Kërkesat teknike

    1. Dukje: White në dritë pluhur të verdhë apo kokrra.
    2. specifikimet:

    Table 1. Specifications of MC&HPMC

    artikuj

    specifikimet

    MC

    HPMC

    MA

    F

    E

    J

    K

    Humbja në tharje,%

    5.0 max

    Mbetje në ndezjen,%

    1.5 max

    metale të rënda, ppm

    20 max

    Arseniku, ppm

    3 max

    pH

    5.0 ~ 8.0

    Viskozitetit (2% solucion), mPa.s

    Në përputhje me specifikimet viskozitetit siç tregohet në tabelën 2.

    specifikim 3. Viskoziteti

    Tabela 2. Specifikimi Viskoziteti i KM & HPMC

    nivel

    varg specifik (2% Sol.), mPa.s

    nivel

    varg specifik (2% Sol.), mPa.s

    5

    4 ~ 6

    4000

    3000 ~ 5600

    15

    12 ~ 18

    8000

    6000 ~ 9000

    25

    20 ~ 30

    10,000

    9000 ~ 12000

    50

    40 ~ 60

    15,000

    12000 ~ 18000

    100

    80 ~ 120

    20,000

    18000 ~ 30000

    400

    300 ~ 500

    40,000

    30000 ~ 50000

    800

    600 ~ 900

    100,000

    85000 ~ 130000

    1500

    1000 ~ 2000

    200,000

    ≥180000

    Shënim : Viskozitetit mund të rregullohen në përputhje me kërkesat e veçanta të konsumatorëve.

    Guide përzgjedhja e produkteve për farmaceutike :

    përdorim llojin e aplikueshme të produktit Tipike Niveli Përdorimi
    laksativ Bulk MA-4000, K-4000, K-100.000 3-30%
    Krem, xhel, dhe ointments MA-4000, E-4000, F-4000, K-4000 1-5%
    Përgatitjet e syrit E-4000 01.-0.5%
    Pika sy përgatitjet MA-4000, F-4000, K-4000 0,1-0,5%
    pezullimin agjent MA-4000, E-4000, K-4000 1-2%
    antacids MA-1500, MA-4000, E-4000, K-4000, K-15000, F-4000 1-2%
    tableta kordon MA-15, E-5, F-50, K-100 0.5-5%
    Konvencional tabletë shtresë E-5, E-15 0.5-5%
    Ashpërim Konvencionale lagur E-5, E-15 2-6%
    Coatings kontrolluara Release E-5, E-15 3-20%
    veshje Tablet E-5, E-15, E-50 0.5-5%
    Kontrolluara Release Matrix Tablets K-100.000, K-15.000, K-4000, E-4000 20-55%

     

    Paketimi

    Produkti është i paketuar në qese polietileni mbyllur në daulle të përbërë fiberboard apo qese letre. Pesha neto është 25 kg / daulle ose 25 kg / qese.

    Produkti duhet të mbahet në qese origjinale dhe të ruhet në vend të thatë dhe të pastër larg nga burimi i ngrohjes dhe nuk vënë së bashku me kimikate të tjera.

     








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